Cell Biology

Active Motif's Zebularine is a DNA methyltransferase inhibitor which binds covalently to methyltransferases. Zebularine re-activates silenced E-cad...

Active Motif's UNC1999 is an orally active, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50 =...

Active Motif's The DNA damage response protein 53BP1 utilizes its tandem tudor domain to recognize dimethylated lysine 20 on histone (H4K20me2), a ...

Active Motif's Potent and selective histone deacetylase 6 (HDAC 6) inhibitor (IC50 = 15 nm; >1000-fold selective against other HDACs and 60-fold...

Active Motif's Triacetyl resveratrol is a resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the...

TouchDown is an innovative precipitation reagent that enables the precipitation of any nucleic acid without the addition of salt, mussel glycogen o...

Active Motif's TC-E-5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.5 uM). It displays no activity against CAR...

Streptavidin Beads are stable, uniform, non-porous spheres bound with highly active streptavidin. They are RNase and DNase free for direct addition...

Streptavidin Beads are stable, uniform, non-porous spheres bound with highly active streptavidin. They are RNase and DNase free for direct addition...

Active Motif's Splitomicin is a Sirtuin inhibitor that was initially shown to inhibit Sir2p (the yeast Sirt1 homolog) and create a conditional phen...

Active Motif's SirtAct is a sirtuin activator (Sirt1). It suppressed TNF-alpha release from THP-1 cells and stimulated adipogenesis in 3T3L1 cells....

Active Motif's Sinefungin is a Nucleoside S-adenosyl-1-methionine analog. It is a potent, competitive methyltransferase (protein, DNA, and RNA meth...

Active Motif's SGC707 is a potent and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3), IC50 = 31 nM and selective ag...

Active Motif's Salermide is a SIRT1 and SIRT2 inhibitor. It exhibits a stronger inhibitory effect on SIRT2 than on SIRT1 in vitro. Salermide induce...

Active Motif's RVX-208 is a potent BET bromodomain antagonist with (IC50 = 0.51 uM for BD2) with approximately 170-fold selectivity over BD1 (ref 1...

Active Motif's RNA Subcellular Isolation Kit provides an efficient method to isolate nuclear and cytoplasmic RNA without cross-contamination. It ca...

Active Motif's RG108 is a non-nucleoside DNA methyltransferase inhibitor (IC50 = 115 nM). It inhibits DNA methylation in human and tumor cell lines...

Protease is active in SDS, EDTA, urea and at high temperatures and is supplied lyophilized. Store at -20C; stable for 6 months.

Poly T gripNA Probe has been optimized to ensure efficient recovery of mRNA from cell lysates and tissue homogenates. It is supplied lyophilized in...

Poly T gripNA Probe has been optimized to ensure efficient recovery of mRNA from cell lysates and tissue homogenates. It is supplied lyophilized in...