Diatech Pharmacogenetics | Blood Cancer | RealTime PCR | MRD Monitoring | EasyPGX Line
Diatech Pharmacogenetics | Blood Cancer | RealTime PCR | MRD Monitoring
EasyPGX Ready is the best-in-class RT-PCR diagnostic solution for oncohematology with a fast and simple workflow based on dry and ready-to-use reagent format.
- One-step real-time PCR
- Validation from RNA extracted from marrow or peripheral blood and leukocyte suspensions (buffy coat)
- TAT from RNA to result < 80 minutes
- Hands-on time <10 minutes
- The same thermal profile shared between all RNA applications.
Kits include:
- 5 quantification standards (105 -101 copies/rxn) calibrated with IRMM ERM-AD623 BCR-ABL1.
- p210 RNA reference standard for results allignments to international scale (%IS)
Maximum sensitivity:
- International scale (%IS) BCR-ABL p210: 0.0015%
- BCR-ABL p190: 0.001%
Flexibility
- Same thermal profile for all EasyPGX qualitative and quantitative RNA kits
- Up to 41 clinical samples for each single run
Automatic data analysis:
- Dedicated software solution with automatic calculation of molecular response (MR) and international scale (%IS).
*Use extraction solutions compatible with those described in the user manual.
EasyPGX Real-Time PCR System
- RT-PCR instrument with 96 wells peltier block
- Up to 6 LED optical channels
- Integrated touch screen
- Automatic data analysis and interpretation software
- System complete of all accessory instrumentation needed for EasyPGX ready workflow
- CE-IVD
EasyPGX Analysis Software: automatic data analysis solution Control Mix and Mutation Assay Analysis Report EasyPGX Analysis Software is the automatic data analysis software dedicated to the use with EasyPGX ready kits.
- CE- IVD
- Complete automated data analysis with a turnaround time < 5 min
- No cloud or external data analysis solution
- Totally automatic data analysis interpretation with the possibility to check raw data in one single software
- Run and sample automatic QC
- Automatic calculation of molecular response (MR) and International Scale (%IS)
- LIMS connectivity
- Data export and report on different common formats
EasyPGX ready BCR-ABL p210 code RT039 (48 test - CE-IVD)
Kit for quantification — by One Step Real-Time RT-PCR — of BCR-ABL fusion variants b2a2 (e13a2) and b3a2 (e14a2), encoding a 210 kDa chimeric protein, in total RNA isolated from peripheral blood or bone marrow.
EasyPGX ready BCR-ABL p190 code RT040 (48 test - CE-IVD)
Kit for quantification — by One Step Real-Time RTPCR — of BCR-ABL fusion variant e1a2 encoding a 190 kDa chimeric protein, in total RNA isolated from peripheral blood or bone marrow.
EasyPGX ready WT1 Quant code RT046 (48 test - CE-IVD)
Kit for quantification — by One Step Real-Time PCR — of Wilms tumour 1 (WT1) gene transcript, in total RNA isolated from peripheral blood or bone marrow and leukocyte suspensions (derived from buffy coat).
