EasyPGX® ready NRAS  cancer research
EasyPGX® ready DPYD cat.no. RT026 (48 test, CE IVD) cancer research devices
EasyPGX® ready DPYD cat.no. RT026 (48 test, CE IVD) cancer research plan

EasyPGX® ready DPYD cat.no. RT026 (48 test, CE IVD)


EasyPGX® ready DPYD cat.no. RT026 (48 test, CE IVD) Main features

Detection, by allelic discrimination, of the DPYD gene polymorphisms DPYD*2A (IVS14+1G>A,c.1905+1G>A,rs3918290), DPYD*13 (c.1679T>G,rs55886062), DPYD D949V (c.2846A>T, rs67376798), DPYD*6 (c.2194G>A, rs1801160) and DPYD IVS10 (c.1129–5923C>G, rs75017182),associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).

EasyPGX® ready DPYD Controls

The kit is provided with the following controls:

  • DPYD WT positive control: Positive control DNA containing a mixture of synthetic wild-type DNA sequences for the DPYD polymorphisms analyzed;
  • DPYD MT positive control: Positive control DNA containing a mixture of synthetic mutant DNA sequences for the DPYD polymorphisms analyzed;
  • Negative control.

Starting material

The kit allows the analysis of genomic DNA extracted from whole blood.

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