HeLa nuclear extract (Anisomycin treated)
Active Motif's HeLa nuclear extract (Anisomycin treated) was prepared from a cell culture of the HeLa human epithelial carcinoma cell line that was treated with anisomycin, an antibiotic and protein synthesis inhibitor. Anisomycin is also a potent inhibitor of the p38/JNK MAPK pathway. The HeLa cell line was originally derived from cells obtained in 1951 from Henrietta Lacks, a cervical cancer patient who eventually died from her cancer. The HeLa cell line is one of the oldest and most commonly utilized immortal cell lines in scientific research. These cells are highly prolific and easily sustainable, allowing for flexibility in their application in various fields of scientific research, including cancer biology, virology, and human disease. To date, over 60,000 publications across various disciplines have referenced the use of HeLa cells.