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NanoBRET Proteasomal Recruitment Starter Kit

by Promega
€ 1,911.40

The NanoBRET Proteasomal Recruitment Starter Kit provides the tools to create target-specific live-cell assays to globally monitor recruitment to the 26S proteasome. This assay can be used to study dynamic increases or decreases in 26S trafficking after cellular treatments, such as small molecules or pathway inducers, that would influence protein stabilization or degradation. These 26S proteasome assays can be particularly useful for the study of targeted degradation compounds because the NanoBRET signal ratio means you can investigate proteasome recruitment while simultaneously monitoring target protein levels to assess degradation.