5-Azacytidine - MyBio Ireland - Active Motif
5-Azacytidine - MyBio Ireland - Active Motif



Regular price€ 0.00
Tax included.

Active Motif's 5-Azacytidine is a specific and potent inhibitor of DNA methyltransferase, DNMT1. It acts as a suicide substrate for methyltransferases after incorporation into DNA, and induces apoptosis in HCT-116 colon cancer cells that is mediated by p53 and its downstream effectors p21 (WAF1) and GADD45. 5-Azacytidine increases stem cell reprogramming efficiency, induces cardiac differentiation of human umbilical cord-derived MSCs, and reverses drug resistance in bladder cancer cells. It is an antileukemic agent that is cell permeable.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.