Bcl3 antibody (pAb)
for Bcl3 antibody (pAb)Application Notes
WB: 1:500 - 1:2,000 dilution
for Bcl3 antibody (pAb)Immunogen
This Bcl3 antibody was raised against a peptide within the C-terminal half of human Bcl3.
for Bcl3 antibody (pAb)Buffer
Rabbit serum containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
for Bcl3 antibody (pAb)References
Bcl3 (B-cell lymphoma 3 protein) functions as a transcriptional co-activator that activates through its association with NFkB homodimers. Bcl3 contains seven ankyrin repeats, which are most closely related to those found in IkB proteins. Bcl3 also functions as a form of IkB specific for the NFkB p50 subunit inhibiting its translocation to the nucleus. The expression of this gene can be induced by NFkB, which forms a part of the autoregulatory loop that controls the nuclear residence of NFkB p50. Bcl3 is overexpressed in a number of cancers, can transform fibroblasts and induce tumors in nude mice, thus implicating Bcl3 as a proto-oncogene.
for Bcl3 antibody (pAb)Positive Control
Active Motif's HeLa whole-cell extract (Catalog No. 40050) can be used as a positive control for Bcl3 antibody.
Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.
for Bcl3 antibody (pAb)Guarantee
This product is guaranteed for 6 months from date of receipt.
This product is for research use only and is not for use in diagnostic procedures.
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FC = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
- WB = Western Blotting