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Histone H3K23pr antibody (pAb), sample

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for Histone H3K23pr antibody (pAb)Application Notes

Published Applications:
See references for more information. Individual optimization may be required.

for Histone H3K23pr antibody (pAb)Immunogen

This antibody was raised against a synthetic peptide corresponding to propionyl-Lys23 human Histone H3.

for Histone H3K23pr antibody (pAb)Buffer

Rabbit serum containing 30% glycerol and 0.035% sodium azide.

for Histone H3K23pr antibody (pAb)References

for Histone H3K23pr antibody (pAb)Background

Propionylation of lysines is a recently identified post-translational modification and has been demonstrated to occur in proteins including histones and non-histone substrates, such as p53. Propionylation of Lys23 of Histone H3 may be catalyzed by the histone acetyltransferase p300 and may be removed by histone deacetylase Sir2. H3K23 proprionylation may play an important role in the epigenetic regulation of cell metabolism.

for Histone H3K23pr antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for Histone H3K23pr antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting