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Control Ab, Anti-CTLA-4

by Promega
€ 603.02

CTLA-4, also known as CD152, is an immune inhibitory receptor constitutively expressed on regulatory T cells (Tregs) and upregulated in activated T cells. CTLA-4 plays a critical role in regulating immune responses to tumor antigens and autoantigens. Control Ab, Anti-CTLA-4 is a control antibody for blocking CTLA-4 for use with the CTLA-4 Blockade Bioassay, a biologically relevant MOA-based assay that can be used to measure the potency and stability of antibodies and other biologics designed to block the CTLA-4/CD80 and CD86 interaction.