HeLa S3 nuclear extract
Active Motif's HeLa S3 nuclear extract was prepared from a cell culture of the HeLa S3 human epithelial carcinoma cell line. The HeLa S3 cell line is a subclone of the HeLa cell line that was originally derived from cells obtained in 1951 from Henrietta Lacks, a cervical cancer patient who eventually died from her cancer. The HeLa cell line is one of the oldest and most commonly utilized immortal cell lines in scientific research. These cells are highly prolific and easily sustainable, allowing for flexibility in their application in various fields of scientific research, including cancer biology, virology, and human disease. To date, over 60,000 publications across various disciplines have referenced the use of HeLa cells. The HeLa S3 cell line has been adapted for growth in suspension (spinner) culture and demonstrates similar characteristics to the parent cell line, including its susceptibility to viral infection and propagation.