The Maxwell 16 miRNA Kit, in combination with the Maxwell 16 MDx Instrument, purifies high-quality total RNA with an enhanced miRNA enrichment. This RNA purification procedure is a simple method with minimal lysate handling before automated purification on the Maxwell 16 MDx Instrument. The low elution volume is used to generate concentrated high-quality RNA suitable for use in downstream applications such as quantitative RT-PCR, arrays and sequencing. The kit contains all the necessary reagents for miRNA extraction in a convenient prefilled cartridge format, maximizing simplicity and convenience.