Anti-Human p75 pAb

Description

• Overview
• Protocols
• Specifications
• Resources

• The p75 neurotrophin receptor (p75^NTR), also known as low-affinity NGF receptor (LNGFR) and p75^LNGFR, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. p75^NTR plays an important role in neurotrophic factor signaling including neuronal apoptosis. Anti-Human p75 pAb provides a valuable tool for understanding the role of p75^NTR in neuronal death. Anti-Human p75 pAb is raised against a recombinant fusion protein produced in E. coli.

  Applications (suggested working concentration)

  • Immunocytochemistry (1–10ug/ml).
  • Immunohistochemistry (1–10ug/ml).
  • Immunoprecipitation (1–10ug/ml).

  Note: This antibody is not recommended for use in Western blot analysis due to potential for cross-reactivity with the fusion tag on the immunogen.

• Certificate of Analysis

  Lookup Certificate of Analysis

  Storage Conditions

  +2C TO +10C

  Use Restrictions

  For Research Use Only. Not for Use in Diagnostic Procedures.

• Resources

  

  Articles

  • Using Promega Antibodies for Neuroscience Research
  

  Citations

  • Lipid rafts mediate the interaction between myelin-associated glycoprotein (MAG) on myelin and MAG-receptors on neurons
    --
    2003 Mol. Cell. Neurosci.