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Abstract We used the NanoBRET™ assay from Promega to identify Myc-Max protein-protein interaction (PPI) inhibitors using the respective proteins tagged with NanoLuc® luciferase (NanoLuc®) and HaloTag® ligands. In addition to this, we used the Myc-Max NanoBiT® complementation assay to validate...

Circulating cell-free DNA (ccfDNA) can be used to monitor tumor burden and monitor disease progress. In this part 3 of 3 ccfDNA webinars, Dr. Gulley discusses variables important to isolating high-quality ccfDNA from plasma samples including anticoagulant, plasma volume and storage length and conditions.