Active Motif has utilized its expertise with ChIP to develop the first commercially available kit to perform ChIP from FFPE samples for use in Next-Generation sequencing. The ChIP-IT FFPE Chromatin Preparation Kit contains specially formulated reagents and protocol guidelines to extract high-quality chromatin from histological slides or tissue sections. Due to the limited yields obtained from FFPE samples, the chromatin must be assayed in the ChIP-IT FFPE Kit, which is the only commercially available ChIP kit with the sensitivity required to enrich for transcription factor or histone protein targets from limited chromatin amounts while producing minimal background signal.
