MODified™ Histone Peptide Array
The MODified Histone Peptide Array is a valuable research tool that can be used to screen antibodies, enzymes and proteins for cross-reactivity or binding interactions with histones and their post-translational modifications. The MODified Histone Peptide Arrays screen 59 acetylation, methylation, phosphorylation, and citrullination modifications on the N-terminal tails of histones H2A, H2B, H3 and H4. Each peptide array contains 384 unique histone modification combinations in duplicate, including up to four separate modifications on the same 19mer peptide. This extensive coverage of histone modifications enables the study not only of individual sites, but also the effects of neighboring modifications on recognition and binding. The simple array protocol works like a Western blot; no special equipment needed.