Skip to content


€ 0.00

Active Motif's AK-7 is a selective Sirt2 inhibitor (IC50 = 15.5 M) that does not bind Sirt1 or Sirt3. It down-regulates cholesterol biosynthesis genes in primary striatal neurons. AK-7 displays neuroprotective effects in Huntington's disease mouse models including improved motor function, extended survival and reduce brain atrophy, all of which were associated with reduced aggregated mutant huntingtin.


Call for Price

I agree to my email being stored and used to receive the newsletter.