Active Motif's Global DNA Methylation - LINE-1 Kit is an ELISA-based assay for the detection and quantification of global DNA methylation (i.e., 5-methylcytosine (5-mC) levels) in human genomic DNA. The assay measures 5-mC levels of Long Interspersed Nucleotide Element 1 (LINE-1) repeats. LINE-1 methylation serves as a surrogate for global DNA methylation levels. The 96-well assay is ideally suited for screening variances in 5-mC levels across different disease states, treatment conditions, clinical outcomes, or environmental factors.
Note: Methylation based assays are research use only and not for individual testing and diagnosis.