As we approach the Christmas & New Year period, we’d like to notify you of our final date for receiving routine orders to facilitate delivery before the Christmas break as Friday 15th December 2023.
The MyBio Team would like to take this opportunity to thank you for your business and continued support. We look forward to meeting you again in 2024.
Active Motif's GSK-J1 is a potent and selective inhibitor of Jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). It is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and, as such, is useful as a standard in vitro assay. A cell permeable ethyl ester analog is also available (Catalog No. 14070).