LightSwitch™ MEG3 Promoter Reporter Vector

Long noncoding RNAs (lncRNAs) have been shown to play important roles in the regulation of both transcription and chromatin organization. But, the promoters of lncRNA genes appear to be regulated differently than those of protein-coding genes. The LightSwitch Luciferase Assay System makes it fast & easy to study lncRNA promoter regulation using the same materials and methods that have been so successful and popular in studying the regulation of protein-coding gene promoters and miRNA-3´UTR interactions. The LightSwitch lncRNA Promoter Products are a collection of widely studied lncRNA promoters that Active Motif has cloned into the LightSwitch Promoter Reporter vector. These are available as sequence-verified, transfection-ready reporter constructs, so you can begin assays to study how these promoters are regulated immediately, without the need to clone, sequence or prepare the DNA. For more complete information, please visit the Active Motif website.