Maxwell® RSC 48 Instrument - MyBio Ireland - MyBio Ireland
Maxwell® RSC 48 Instrument - MyBio Ireland - MyBio Ireland

Maxwell® RSC 48 Instrument

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  • Protocols
  • Specifications
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Automated Nucleic Acid Purification of 1 to 48 Samples

  • High-quality nucleic acid purification with minimal steps and less hands-on time
  • Purifies 1–48 samples in a single run
  • Intuitive software and integrated vision system for detecting and preventing deck tray setup errors


Catalog number selected: AS8500

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High-quality nucleic acids with less hands-on time

The Maxwell® RSC 48 Instrument is a compact, automated nucleic acid purification platform that processes up to 48 samples simultaneously. Using Maxwell® RSC prefilled cartridges, the Maxwell® RSC 48 Instrument brings the same consistent, reliable purification of DNA or RNA from a variety of sample types and a higher throughput. The intuitive graphical interface makes the instrument easy to use. The integrated vision system with its large LED indicator reduces the potential for user error by detecting proper cartridge placement and lets you know before a run starts if there is an issue. An integrated Bar Code reader makes it easy to track samples.


No clogging worries with a paramagnetic particle mover

The Maxwell® RSC System starts with cartridges prefilled with reagents and paramagnetic particles, ready for your samples. After sample addition, the Maxwell® RSC moves the paramagnetic particles and associated nucleic acids through multiple steps ultimately yielding highly pure RNA or DNA in 30–100µl.

Because the Maxwell® RSC is a magnetic particle mover, not a liquid handler, it offers advantages over other automated systems. There is minimal risk of cross-contamination because no liquid handling or splashing happens during sample processing. With no clogs and fewer breakdowns, there are fewer disruptions to your workflow.


Easy-to-use interface simplifies your workflow

Track samples easily

The integrated barcode reader records important information such as sample ID, kit ID and kit lot number.

Touch screen to begin the process

The intuitive touch screen interface lets you easily set up your purification run.

Prepare sample cartridges

Place prepared cartridges in the Maxwell® RSC 48. Press “Start” to purify 1–48 samples using the selected kit’s preprogrammed method.

Start run with confidence

The integrated vision system detects proper cartridge setup along with a large LED indicator and audible alarm, giving you confidence your extraction is running smoothly.

Works with multiple sample types

DNA Purification

DNA purified with the Maxwell® RSC System is compatible with a wide range of downstream applications such as Sanger and next generation sequencing, arrays and digital PCR.


Maxwell® RSC Whole Blood DNA Kit »
Extracts DNA from larger sample sizes (up to 500µl) of whole blood without preprocessing

Maxwell® RSC Blood DNA Kit »
Extracts higher yields of DNA from up to 300µl of whole blood following Proteinase K treatment


Maxwell® RSC DNA FFPE Kit »
Extracts DNA from formalin-fixed paraffin embedded (FFPE) tissue sections


Maxwell® RSC ccfDNA Plasma Kit »
Extracts ccfDNA from plasma

Maxwell® RSC Viral Total Nucleic Acid Purification Kit »
Extracts viral total nucleic acid (RNA and DNA) from serum, plasma and other samples

RNA Purification

RNA purified with the Maxwell® RSC System is compatible with downstream applications RT-PCR.


Maxwell® RSC simplyRNA Blood Kit »
Purifies total RNA from 2.5ml of fresh whole blood


Maxwell® RSC simplyRNA Cells Kit »
Purifies total RNA from fresh or frozen cells


Maxwell® RSC RNA FFPE Kit »
Extracts RNA from formalin-fixed paraffin embedded (FFPE) tissue sections


Maxwell® RSC simplyRNA Tissue Kit »
Purifies total RNA from up to 20mg of tissue

Maxwell® RSC miRNA Tissue Kit »
Purifies total RNA, including miRNA, from mammalian tissue samples


Maxwell® RSC Viral Total Nucleic Acid Purification Kit »
Extracts viral total nucleic acid (RNA and DNA) from serum, plasma and other samples

Instrument Specifications

Processing Time: 30–60 minutes

Sample Capacity: 1–48 Samples; (2) 24 position, removable trays

Dimensions: (W × D × H): 21 × 20 × 12.5 inches (533 × 508 × 317.5 mm)

Weight: 70 lbs (31.75 kg) est.

Main Power Voltage: 100–240V AC, 50/60Hz; autosensing; 4 Amps

Operating Environment: 15–25°C

Service and Warranty: 1-year limited warranty on parts and labor. Extended service contracts

UV-Bulb: Average lifetime approximately 6,000 hours

Instrument Standard Components


A. Maxwell® RSC 48 Instrument

B. Tablet PC preloaded with Maxwell® RSC 48 Application Software

C. Power Supply for Tablet PC (Power Cord for Tablet PC provided separately)

D. USB Cable - Maxwell® RSC 48 Instrument to Tablet PC

E. Power Cable for Maxwell® RSC 48 Instrument (provided separately)

F. Maxwell® RSC 48 Deck Trays (2)

G. Hand held barcode reader

H. USB cable for connection of the Maxwell® RSC 48 Instrument to the barcode reader

UV Bulb (installed)

Quick Start Guide

Setup Guide

Service and Support

One Call Supports It all

Promega supplies both the reagents and the instrument, so one call to Promega answers any questions you may have about assay chemistries or instrument performance.

Contact Technical Services

Ensure Minimal Instrument Downtime

  • Field Support and Loaner Programs
  • Service Packages
  • IQ and OQ Packages

Warranty and Service Agreements

  • Backed by a one-year warranty.
  • Additional warranty and service agreements are available.
  • For more information contact Promega Technical Services.

Accessories Available Separately

Additional deck trays, plungers and an optional bar code reader are available for purchase separately.

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Certificate of Analysis

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

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