Raji nuclear extract

Active Motif's Raji nuclear extract was prepared from cell cultures of the Raji Burkitt's Lymphoma cell line. This lymphoblastoid cell line was derived from a Nigerian patient with Burkitt's lymphoma and is the first continuous cell line of hematopoietic origin. These cells are most commonly used in studies related to hematology and related cancers, such as leukemia and lymphoma. Raji cells are a line of Epstein-Barr virus (EBV)-transformed lymphocytes and thus harbor latent EBV genomes and various chromosomal translocations, making them an ideal source for material for cytogenetic analysis. In addition, these cells express numerous surface Fc receptors and are routinely used for detection and analysis of immune complexes.