Twist Bioscience NGS | Alliance Panels | Twist Alliance VCGS Exome

Where routine testing has failed to provide a diagnosis, physicians often turn to DNA sequencing panels for answers, particularly when a heritable disease is suspected. But without expert guidance, it can be hard to know which panel is the right panel.
Drawing on decades of experience in clinical genomics, Victorian Clinical Genetics Services (VCGS) has partnered with Twist to design a diagnostic panel—Twist Alliance VCGS Exome - 40.1 MB—that covers the whole exome, with dedicated coverage boosting over clinically relevant genes (Mendeliome). In designing this panel, special care was given to ensuring additional coverage of clinically relevant loci that fall outside the gene coding regions traditionally targeted by exomes (i.e. known pathogenic loci in non-coding regions).
The Twist Alliance VCGS Exome - 40.1 MB panel is a best-in-class, highly uniform panel that can help streamline the identification of heritable disease-linked alleles, be it through carrier screening or pre- and post-natal testing.

Note: The Twist Alliance VCGS Exome - 40.1 MB content has not been fully validated through the complete Twist workflow. For recommendations on assay set-up, please contact Twist Customer Support.

Note: The Twist Alliance VCGS Exome - 40.1 MB is not ISO-13485 certified.