Twist Bioscience NGS | Long Read Sequencing Panels
Twist Bioscience Next Generation Sequencing
Long Read Sequencing Panels
Combine Twist target enrichment with long read sequencing to efficiently sequence important genomic regions at scale. Pre-designed Twist Alliance panels enable researchers to capture target regions in a cost-effective and high throughput manner. Customers can also develop fully customizable and scalable panels with their own designs.
Panels Built for Long Read Sequencing
- Probes optimized for high uniformity and sequencing efficiency
- Balanced coverage across difficult-to-sequence or difficult–to-map regions
- Custom panels with cost-effective and flexible scaling
Long Read Sequencing at Scale
- Protocol optimized for long fragment enrichment
- Pack more samples in a single sequencing run
- Study targeted regions across large cohorts
Accurate Variant Calling with Targeted HiFi Sequencing from PacBio
- High accuracy variant calling of SNPs, SVs and indels
- Unambiguous haplotype resolution and long-range phasing
- Compatible with Sequel IIe and Revio Systems
Twist Alliance Dark Genes Panel
Enables sequencing of genes that are difficult or impossible to fully sequence with short read technology.
- Targets 389 genes (20 Mb)
- Key targets include GBA, SMN1/2
Full-gene phasing and no coverage gap in the GBA gene
Twist Alliance Long-Read PGx Panel
Focus on important genes in pharmacogenomics that are critical to drug metabolism and patient therapeutic response.
- Targets 49 genes (2 Mb)
- Key targets include CYP2D6, HLA-A, HLA-B
Accurate star allele calling at CYP2D6
SKUs
- 106747 - Twist Alliance Dark Genes Panel, 2 Reaction Kit
- 106748 - Twist Alliance Dark Genes Panel, 12 Reaction Kit
- 106914 - Twist Alliance Dark Genes Panel, 96 Reaction Kit
- 106749 - Twist Alliance Long-Read PGx Panel, 2 Reaction Kit
- 106750 - Twist Alliance Long-Read PGx Panel, 12 Reaction Kit
- 106915 - Twist Alliance Long-Read PGx Panel, 96 Reaction Kit
DOWNLOADS
PROTOCOL
- Long Read Library Preparation and Standard Hyb v2 Enrichment - READ NOW
WEBINAR
- Long-Read Capture with Twist Target Enrichment - WATCH WEBINAR
DATA FILES
* For research use only. Not for diagnostic procedures.
