ATAC-Seq is a rapid assay that enables analysis of epigenetic profiles across the genome by identification of regions that have open or accessible chromatin states. Active Motif's ATAC-Seq Kit provides the reagents necessary to produce 16 unique sequencing-ready Illumina-compatible ATAC-Seq libraries from 20-30 mg tissue or 50,000-100,000 cells per reaction. The optimized protocol guides you through the steps for sample preparation, tagmentation and library preparation, yielding next-gen sequencing-ready libraries that can be multiplexed in a single flow cell sequencing run.