The pAM_gRNA Vector is used with Active Motif's enChIP Kit (engineered DNA-binding molecule-mediated chromatin immunoprecipitation; Catalog No. 53125), which utilizes the CRISPR/Cas system to target specific genomic regions for investigation of associated DNA-binding interactions. The enChIP Kit makes it possible to evaluate cis- and trans-interacting chromosomal looping events. Additionally, the enChIP Kit can be used to study off-target gRNA binding sites to determine the quality of gRNA design prior to use in genome editing experiments. For more complete information, please visit the Active Motif website.